A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC
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چکیده
منابع مشابه
A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC
High levels of BAALC, ERG, EVI1 and MN1 expression have been associated with shorter overall survival in AML but standardized and clinically validated assays are lacking. We have therefore developed and optimized an assay for standardized detection of these prognostic genes for patients with intermediate cytogenetic risk AML. In a training set of 147 intermediate cytogenetic risk cases we perfo...
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Analysis of BAALC gene Expression as prognosis factor in Pediatric Acute Myeloid Leukemia in Iran
Background:Brain and Acute Leukemia Cytoplasmic (BAALC) is a gene which its expression is confined to progenitor cells; therefore, no expression has been illustrated in mature cells of bone marrow or white blood cells (WBC). In addition, high BAALC expression is associated with poor prognosis in Acute Myeloid Leukemia (AML) individuals and is considered as an important risk factor in Cyto...
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ژورنال
عنوان ژورنال: Experimental Hematology & Oncology
سال: 2013
ISSN: 2162-3619
DOI: 10.1186/2162-3619-2-7